RECOMBINANT PLASMID DNA 36K-PVH, CODING SYNTHESIS OF IMMUNOGENIC PROTEIN 36K OF SMALLPOX VACCINE, STRAIN LIVP, AND STRAIN OF BACTERIA ESCHERICHIA COLI - A PRODUCER OF THIS PROTEIN

摘要

the invention u043eu0442u043du043eu0441u0438u0442u0441u00a0 biotechnology, including genetic engineering and medicine. purpose u0438u0437u043eu0431u0440u0435u0442u0435u043du0438u00a0 u00a0u0432u043bu00a0u0435u0442u0441u00a0 a strain E.COLI - u043fu0440u043eu0434u0443u0446u0435u043du0442u0430 u0438u043cu043cu0443u043du043eu0433u0435u043du043du043eu0433u043e protein 36 to u043eu0441u043fu043eu0432u0430u043au0446u0438u043du044b u043bu0438u0432u043f virus strain. designed u0432u0435u043au0442u043eu0440u043du0430u00a0 u043fu043bu0430u0437u043cu0438u0434u0430 36 - PVH, u0441u043eu0434u0435u0440u0436u0430u0449u0430u00a0 fla - gene, providing resistance to u0430u043cu043fu0438u0446u0438u043bu043bu0438u043du0443 and lac z gene with its own u043fu0440u043eu043cu043eu0442u043eu0440u043eu043c. in the transformation of cells of e.COLI u0432u043cu043d 71 - 18 u043fu043bu0430u0437u043cu0438u0434u043eu0439 36 - PVH are strain - a producer u0445u0438u043cu0435u0440u043du043eu0433u043e protein which possesses the specificity of viral u0430u043du0442u0438u0433u0435u043du043du043eu0439, u0441u0432u00a0u0437u044bu0432u0430u0435u0442u0441u00a0 with serum antibodies to u0440u043eu0432u0438 from u043fu0435u0440u0435u0431u043eu043bu0435u0432u0448u0438u0445 animals and can be used u0434u043bu00a0 diagnostic purposes. u0445u0438u043cu0435u0440u043du044bu0439 protein u00a0u0432u043bu00a0u0435u0442u0441u00a0 u0438u043cu043cu0443u043du043eu0433u0435u043du043du044bu043c.strain of bacteria containing u043fu043bu0430u0437u043cu0438u0434u0443 36 - PVH, u0437u0430u0434u0435u043fu043eu043du0438u0440u043eu0432u0430u043d in u0432u0441u0435u0441u043eu044eu0437u043du043eu0439 collection of industrial microorganisms number in 4743. 2 u0441.u043f.u0444 - lu, 1 table.