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Modulation of aids virus-related events by double-stranded RNAs

机译:双链RNA调节艾滋病病毒相关事件

摘要

The use of mismatched dsRNA, e.g., AMPLIGEN® for the manufacture of compositions for use in the selective activation of a latent natural defense system within human cells, both cells already infected with AIDS virus as well as cells at risk to infection. Specific treatments for various clinical phase of the biological continuum of AIDS virus-related events ranging from subtle, early immunological lesions to advanced disease are described. Prophylaxis or prevention of AIDS virus related events, such as by introduction of mismatched double-stranded RNA into various blood products or biological fluids to be used in man (e.g., blood transfusion) or around man (e.g., dialysis programs) are also described.
机译:错配的dsRNA(例如AMPLIGEN®)用于制造组合物的用途,该组合物用于选择性激活人细胞内潜在的自然防御系统,既已感染AIDS病毒的细胞又有感染风险的细胞。描述了从细微,早期的免疫损伤到晚期疾病的,与艾滋病病毒有关的生物连续性各个临床阶段的具体治疗方法。还描述了预防或预防AIDS病毒相关事件的方法,例如将不匹配的双链RNA引入各种血液制品或人类(例如输血)或人类周围(例如透析程序)使用的生物液体中。

著录项

  • 公开/公告号US5063209A

    专利类型

  • 公开/公告日1991-11-05

    原文格式PDF

  • 申请/专利权人 HEM RESEARCH INC.;

    申请/专利号US19900565174

  • 发明设计人 WILLIAM A. CARTER;

    申请日1990-08-10

  • 分类号A61K31/70;A61K37/00;

  • 国家 US

  • 入库时间 2022-08-22 05:45:38

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