2,2'-BIS(DIPHENYLPHOSPHINO)-5,5',6,6',7,7',8,8'-OCTAHYDRO-1,1'-BINAPHTHYL AND TRANSITION METALLIC COMPLEX CONTAINING THE SAME AS LIGAND

摘要

NEW MATERIAL:2, 2'-Bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'- binaphthyl expressed by formula I. USE:A ligand of a catalyst, containing a complex thereof with a transition metal such as rhodium, ruthenium, iridium, palladium or nickel, having excellent catalytic activity as the catalyst for various asymmetric syntheses such as asymmetric hydrogenation, asymmetric isomerization and asymmetric silylation and capable of producing optically active substances of high optical purity. PREPARATION:A compound expressed by formula III (X1 is halogen) is hydrogenated in the presence of a ruthenium-carbon catalyst to provide a new substance expressed by formula IV, which is then allowed to react with metallic magnesium in the presence of the ruthenium-carbon catalyst to afford a new substance expressed by formula V. The resultant substance expressed by formula V is subsequently reacted with a diphenylphosphinyl halide to provide a new substance expressed by formula VI, which is then optically resolved and subsequently reduced with trichlorosilane to afford the objective optically active substance expressed by formula I.