METHOD FOR DETERMINING PRESENCE OF ANTIGEN WHICH IS SPECIFIC IN ALZHEIMER'S DISEASE

摘要

PURPOSE: To determine the presence of a specific antigen for Alzheimer disease in a sample by bringing the sample into contact with a first antibody, generating a first complex, recovering the first complex, bringing the first complex into contact with the second antibody, generating a second complex, and detecting the presence of the second complex. CONSTITUTION: A sample is brought into contact with a first antibody capable of being bonded to an antigen toward the antigen deciding factor in the antigen to generate a first complex, and the first complex is recovered from the sample. Then, the recovered complex is brought into contact with at least the second antibody capable of being bonded to the antigen in the first complex directed toward the second antigen deciding factor (the second antigen deciding factor may be the same as the initial antigen deciding factor) in the antigen to be bonded to the antigen to generate the second complex made of the antigen bonded to the first and second complexes. The presence of the second complex is detected to determine the presence of the specific antigen for Alzheigher disease in the sample.