DIRECT TRANSFUSIBLE O OR AH TYPE ERYTHROCYTE-CONTAINING COMPOSITION

摘要

Am composition comprising type 0 erythrocyte free of P1 antigenicity; a method of converting erythrocytes of the B antigen type to erythrocytes of the H-antigen type which comprises:… A. equilibrating said erythrocytes to a pH of 5.7-5.8;… B. thereafter contacting the so-equilibrated erythrocytes with an enzyme for a period sufficient to convert the B antigen in said erythrocytes to the H-antigen;… C. thereafter removing said enzyme from said erythrocytes and… D. re-equilibrating said erythrocytes to a pH of 7.2-7.4. …??The specification discloses conversion of the B antigens in human and animal blood to the H antigen (0 cells).