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N,O-SULFATED HEPAROSANES, PROCESS OF THEIR PREPARATION AND PHARMACEUTICALCOMPOSITIONS CONTAINING SAID N,O-SULFATED HEPAROSANES

机译:N,O硫酸化肝素,其制备过程和包含所述N,O硫酸化肝素的药物组合物

摘要

N,O-Sulphated heparosans consisting of chains or of a mixture of chains with a molecular mass of between 1500 and 15000 Da, characterised by a repeated disaccharide structure of formula I: IMAGE in which - E denotes an acetyl group in 0 to 80 % of the disaccharide units of the said N,O-sulphated heparosan, and a sulphate group and optionally a hydrogen atom in the remaining disaccharide units, - G denotes a hydrogen atom and a sulphate group, and the pharmaceutically acceptable salts of the said N,O-sulphated heparosans. Medication.
机译:N,O-硫酸化肝素,由分子量为1500至15000 Da的链或链的混合物组成,特征在于重复的式I的二糖结构:,其中-E表示0至0的乙酰基所述N,O-硫酸化肝素的二糖单元的80%,以及在剩余的二糖单元中的硫酸基和任选的氢原子,-G表示氢原子和硫酸基,以及所述药物的可药用盐N,O硫酸化肝素。药物。

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