Process for the preparation of alpha-L-aspartylphenylananine methyl ester hydrochloride using isolated N-formyl-L-asparagine anhydrides

摘要

A process for the preparation of alpha -L-aspartyl-L-phenylalanine methyl ester hydrochloride ( alpha -APM(HCl)) is disclosed. alpha -APM(HCl) is an intermediate in the preparation of aspartame.