A process for preparing an immunoglobulin comprising heavy and light chain, with specificity for a particular identified antigen, DNA sequences encoding same, replicable expression vectors for the DNA sequences and recombinant host cells transformed with the vectors

摘要

Recombinant DNA techniques are used to produce both immunoglobulins which are analogous to those normally found in vertebrate systems and to take advantage of these gene modification techniques to construct chimeric or other modified forms.