首页> 外国专利> Analogifremgangsmaade for the preparation of 1,4-dihydropyridine derivatives or pharmaceutically acceptable acid addition salts thereof, and 1,4-dihydropyridine derivatives for use as starting material in the process

Analogifremgangsmaade for the preparation of 1,4-dihydropyridine derivatives or pharmaceutically acceptable acid addition salts thereof, and 1,4-dihydropyridine derivatives for use as starting material in the process

机译:用于制备1,4-二氢吡啶衍生物或其药学上可接受的酸加成盐的类似物,以及在该方法中用作原料的1,4-二氢吡啶衍生物

摘要

1,4-Dihydropyridine derivatives of the formula: IMAGE (I) and their pharmaceutically acceptable acid addition salts; where R is aryl or heteroaryl; R1 and R2 are each independently C1-C4 alkyl or 2-methoxyethyl; Y is -(CH2)2-, -(CH2)3-, -CH2CH(CH3)- or -CH2C(CH3)2-; R3 is hydrogen or an organic substituent are useful in treating or preventing heart conditions or hypertension.
机译:式:<图像>(I)的1,4-二氢吡啶衍生物及其药学上可接受的酸加成盐;其中R是芳基或杂芳基; R1和R2各自独立地为C1-C4烷基或2-甲氧基乙基; Y为-(CH 2)2-,-(CH 2)3-,-CH 2 CH(CH 3)-或-CH 2 C(CH 3)2-。 R 3是氢或有机取代基可用于治疗或预防心脏病或高血压。

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