1- (hydroxymethyl) -1,6,7, 11B-tetrahydro-2H, 4H- (1,3) -OXAZINO- OR -TIAZINO (4,3-a) isoquinoline derivatives and pharmaceutical compositions containing them

摘要

The invention relates to 1-(hydroxymethyl)-1,6,7,11b-tetrahydro-2H,4H-[1,3]oxazino- or -thiazino-[4,3-a]isoquinoline derivatives of the formula (I), IMAGE (I) wherein R1 and R2 are alkoxy having from 1 to 6 carbon atoms, X is oxygen or sulfur, Y is =O, =S or an =NR3 group, wherein R3 is hydrogen, alkyl having from 1 to 6 carbon atoms, cycloalkyl having from 3 to 8 carbon atoms or optionally substituted phenyl, and acid addition and quaternary salts thereof.