RECOMBINANT DNA THAT CAN EXPRESS STEP HYLOCINASE AND IS DERIVED FROM A TEMPERATIVE PHAG OF STAPHYLOCOCCUS AUREUS, PROCEDURE FOR PREPARING RECOMINANT DNA, AND PROCEDURE FOR PREPARING PROCESS

摘要

Novel recombinant DNA and a coliform bacillus are provided which are useful for the industrial production of staphylokinase, a fibrinolytic enzyme. A process is provided for the production of staphylokinase by cultivating the bacillus. A host coliform bacillus has a vector introduced into its phenotypycally expressible genotype, which vector recombinant DNA carrying genetic information encoded for the production of staphylokinase has been inserted, said DNA being derived from digestion of temperate phage DNA of Staphylococcus aureus.