Novel tricyclic triazolopyrimidine compounds represented by the formula CHEM wherein A represents = @@ or =N-; A' represents a hydrogen atom, alkyl or a halogen-substituted alkyl, R represents an alkyl, a halogen-substituted alkyl, an alkenyl, a halogen-substituted alkenyl, or a cycloalkyl or a cycloalkenyl, each of which may be substituted with one or more substituents selected from hydroxyl, an alkyl, an alkoxy, a halogen, an amino, and a halogen-substituted alkyl; and X represents a single bond, or an alkylene or an alkenylene, each of which may be substituted with one or more substituents selected from alkoxy and halogen are disclosed. These compounds have an excellent anti-allergic activity and are useful for treatment and prophylaxis of allergic diseases.
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