首页> 外国专利> ABSORBENT PRODUCT CONTAINING MONO- OR DIESTERS OF A POLYHYDRIC ALCOHOL AND A C8-18 FATTY ACID HAVING AT LEAST ONE FREE HYDROXYL GROUP IN SUFFICIENT AMOUNT TO INHIBIT THE PRODUCTION OF ENTEROTOXINS A, B AND C BY STAPH. AUREUS

ABSORBENT PRODUCT CONTAINING MONO- OR DIESTERS OF A POLYHYDRIC ALCOHOL AND A C8-18 FATTY ACID HAVING AT LEAST ONE FREE HYDROXYL GROUP IN SUFFICIENT AMOUNT TO INHIBIT THE PRODUCTION OF ENTEROTOXINS A, B AND C BY STAPH. AUREUS

机译:含有单醇或多酚,三羧酸和C8-18脂肪酸的消化产物,它们至少有一个游离羟基,足以抑制STAPH生产肠毒素A,B和C。金黄色

摘要

Absorbent products, especially catemenial tampons, for absorbing body fluids, such as menstrual fluid, blood and wound exudates, comprise an amount of a compound effective to inhibit the production of Enterotoxin A, Enterotoxin B and/or Enterotoxin C by Staphylococcus aureus bacteria when the products are brought into contact with the bacteria. The compositions of this invention are also useful to inhibit production of Streptococcal pyrogenic exotoxins A, B and C, as well as hemolysins produced by Groups A, B, F and G streptococci in solution as well as being expected to be effective to inhibit such toxin and hemolysin production when used in conjunction with absorbent products. The compound is selected from the group consisting of monoesters of a polyhydric aliphatic alcohol and a C8-C18 fatty acid; diesters of a polyhydric aliphatic alcohol and a C8-C18 fatty acid; and mixtures thereof. The monoesters and diesters have at least one hydroxyl group associated with their aliphatic alcohol residue.
机译:用于吸收诸如月经,血液和伤口渗出液之类的体液的吸收剂产品,尤其是月经棉塞,包含一定量的化合物,该化合物可有效抑制金黄色葡萄球菌细菌产生肠毒素A,肠毒素B和/或肠毒素C。产品与细菌接触。本发明的组合物还可用于抑制链球菌热原性外毒素A,B和C的产生,以及由A,B,F和G族的链球菌在溶液中产生的溶血素,并有望有效地抑制这种毒素。与吸收性产品结合使用时产生溶血素。该化合物选自多元脂族醇和C8-C18脂肪酸的单酯;多元脂族醇和C8-C18脂肪酸的二酯;及其混合物。单酯和二酯具有至少一个与其脂族醇残基缔合的羟基。

著录项

  • 公开/公告号NO914238L

    专利类型

  • 公开/公告日1992-05-04

    原文格式PDF

  • 申请/专利权人 MCNEIL-PPC INC;

    申请/专利号NO19910004238

  • 发明设计人 BROWN-SKROBOT SUSAN KAY;

    申请日1991-10-29

  • 分类号A61K31/23;

  • 国家 NO

  • 入库时间 2022-08-22 05:34:44

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