PURINE SUBSTITUTED CYCLOPENTANE DERIVATIVES AS CARBOCYCLIC ANALOGUES OF NUCLEOSIDES, AND PHARMACEUTICAL COMPOSITIONS

摘要

The present invention provides the compounds of formula (I) CHEM and salts and solvates thereof wherein R1 represents a hydrogen or fluorine atom or a hydroxy group, R2 represents a fluorine atom or a hydroxyl or C1-6alkoxy group and B represents a purine base, and describes processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of viral infections, particularly those caused by the Herpetoviridae.