RANDOM COPOLYMERS OF P-DIOXANONE,LACTIDE AND/OR GLYCOLIDE AS COATING POLYMERS FOR SURGICAL FILAMENTS

摘要

Low molecular weight absorbable copolymers of p-dioxanone with lactide and/or glycolide are used as coatings for surgical filaments to improve tactile smoothness and tie-down properties. These copolymers are prepared by reacting p-dioxanone with lactide and/or glycolide in the presence of an initiator such as a mono- or polyhydric alcohol or a hydroxy acid.