dierytromycin and dikolinsalterna / 3s (z) / / 2 / / 1 - (2 - amino - 4 - thiazolyl) - 2 - / / 2,2-dimethyl - 4 - oxo - 1 - (sulfooxy) - 3 - amino - 2 - azetidinyl / / / / / oxoetyliden amino oxy - aettiksyra anvaendbara in the treatment of bacterial infections in daeggdjur and foerfarande foer framstaellning daerav

摘要

In accordance with the present invention an orally active monosulfactam antibiotics having a crystalline structure and thereby improved stability are disclosed. The antibiotics comprise the dierythromycin (M(+)=erythromycin.H(+)) salt or the dicholine (M(+)=HOCH2CH2N(+)(CH3)3) salt of the acid (M(+)=H(+)) having the formula IMAGE that is, [3S(Z)]-2[[[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfooxy )-3-azetidinyl]-amino]-2-oxoethylidene]amino]oxy]acetic acid.