derivatives 17beta oh 19 nor steroid replaced in 17alfa, process of preparation, their use as medicaments and the pharmaceutical compositions comprising them

摘要

Novel 19-nor steroids of the formula IMAGE I wherein R' is selected from the group consisting of propyl, propenyl, iodoethenyl, iodoethynyl or -C 3BOND C-CH2-Hal1, Hal1 is selected from the group consisting of fluorine, chlorine and bromine and their non-toxic, pharmaceutically acceptable acid addition salts having a remarkable antiglucocorticoid and antiprogestomimetic activity.