composition for soup of shrimp water which uses the whole body of the crustacean, and process for its preparation.

• 1. 一种治疗共济失调的组合物以及使用该组合物制备百草养元汤的方法 [P] . 中国专利： CN109568547A . 2019-04-05
• 2. 一种活络除颤组合物以及使用该组合物制备活络除颤汤的方法 [P] . 中国专利： CN109620946A . 2019-04-16
• 3. composition for soup of shrimp water which uses the whole body of the crustacean, and process for its preparation. [P] . IT9048463D0 . 1990-11-12

  机译： 一种使用甲壳动物全身的虾水汤的组合物及其制备方法。

• 4. Composition for freshwater crayfish soup which uses the entire body of the crustacean, and method for its preparation [P] . IT1243540B . 1994-06-16

  机译： 利用甲壳动物全身的淡水小龙虾汤用组合物及其制备方法

• 5. AN IMPROVED COMPOSITION FOR FEEDING SHRIMP HAVING PROLONGED STABILITY IN WATER AND RESISTANT TO EASY DISINTEGRATION OR DISPERSION IN WATER AND A PROCESS FOR MAKING THE SAME [P] . IN166557B . 1990-06-09

  机译： 一种改进的用于给虾的组合物，该组合物在水中具有很强的稳定性，并且易于在水中分解或分散，并且制备方法相同

• 1. Tadpole Shrimps-A General Review of the Little Known Crustaceans of Ephemeral Waterbodies [J] . MichałRogacki, Adam Brysiewicz 生态学研究(英文) . 2021,第002期
• 2. Strontium isotope composition of the Arno River Valley waters (Tuscany, Italy) as a natural tracer of water-rock interaction and mixing processes [J] . 中国地球化学学报（英文版） . 2006,第0z1期
• 3. Shallow Water Body Data Processing Based on the Seismic Oceanography [J] . LIU Huaishan, HU Yi, YIN Yanxin, 中国海洋大学学报（英文版） . 2013,第003期
• 4. Effect of Stocking Density on Water Quality and (Growth, Body Composition and Plasma Cortisol Content) Performance of Pen-Reared Rainbow Trout (Oncorhynchus mykiss) [J] . LIU Qun, HOU Zhishuai, WEN Haishen, 中国海洋大学学报（英文版） . 2016,第004期
• 5. The global health issues: crustaceans, with an emphasis onpenaeid shrimp [C] . D.V. Lightner, R.M. Redman The OIE Giobal Conference on Aquatic Animal Health . 2012
• 6. Attenuating the Antibody Reactivity of the Shrimp Major Allergen (Tropomyosin) using Food Processing Methods [D] . Lasekan, Adeseye O. 2017
• 7. A new calmanostracan crustacean species from the Cretaceous Yixian Formation and a simple approach for differentiating fossil tadpole shrimps and their relatives [O] . Philipp Wagner, Joachim T. Haug, Carolin Haug 2019
• 8. Figure 5 from: Bauer RT, Okuno J, Thiel M (2014) Inferences on mating and sexual systems of two Pacific Cinetorhynchus shrimps (Decapoda, Rhynchocinetidae) based on sexual dimorphism in body size and cheliped weaponry. In: Wehrtmann IS, Bauer RT (Eds) Proceedings of the Summer Meeting of the Crustacean Society and the Latin American Association of Carcinology, Costa Rica, July 2013. ZooKeys 457: 187-209. https://doi.org/10.3897/zookeys.457.6512 [O] . Bauer, Raymond, Okuno, Junji, Thiel, Martin 2014

• 1. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
• 2. 专利文献综述试论《一种通络止痛的中药组合物及其制备方法》 [C] . 韩济世 . 庆祝建国60周年中医药名家高层论坛 . 2009
• 3. “黄龙四苓汤”中大黄、龙胆提取物制备方法研究 [A] . 穆亚琦 . 2017