4 (R) SUBSTITUTED 6 (S) -PHENOXYMETHYL-, 6 (S) -BETA-PHENYLAETHYL- AND 6 (S) -BETA-STYRYL-TETRAHYDROPYRAN-2-ONE, A HIGHLY STEREOSELECTIVE METHOD FOR PERSONALIZING YOUR PERSONAL THESE CONNECTIONS AND THEIR USE.

摘要

4(R)-substituted 6(S)-phenoxymethyl-, 6(S)- beta -phenylethyl- and 6(S)- beta -styryltetrahydropyran-2-ones of the formula V …IMAGE… in which R7, R8 and A have the meanings indicated, the corresponding open-chain hydroxycarboxylic acids, and their pharmacologically tolerable salts and esters are used as medicaments. Novel alpha , beta -unsaturated lactones for the preparations of the compounds of the formula V are additionally described.