REAGENT SYSTEM FOR IMMUNOLOGICALLY ASSAYING COMPLEX OF HUMAN PLASMINOGEN ACTIVATOR INHIBITOR AND HUMAN TISSUE PLASMINOGEN ACTIVATOR, AND ASSAY KIT THEREFOR

摘要

A reagent system for immunologically assaying a human plasminogen activator inhibitor l-human tissue plasminogen activator complex in a human assay sample by using a first antibody bound to an insoluble solid carrier and a labelled second antibody, one of the antibodies being monoclonal antibody JTI-3 or JTI-4 against the human plasminogen activator inhibitor 1 or an equivalent fragment thereof and the other being monoclonal antibody JTA-1 against the human tissue plasminogen activator or an equivalent fragment thereof; an assay kit therefor, a method of assaying it, monoclonal antibodies therefor, and the use of these antibodies. In accordance with this, the amount of the above complex in a human assay sample can be assayed with high sensitivity.