Process for the enhancement of riboflavin levels in spray-dried riboflavinfermentation extracts

摘要

The process is characterised in that the dissolution of the cells contained in the riboflavin-containing fermenter discharge is induced by specific production or activation of enzymes which break down cell walls and degrade proteins. This so-called autolysis, in the case of the riboflavin-producing strains Ashbya gossypii, Eremothecium ashbyli and other microorganisms, can be induced by incubation at 35 to 55 DEG C, with substantial exclusion of oxygen, for 6 to 28 hours.