2,5-Diaryl-1,3,4-oxadiazole hydroxyester, hydroxyacide and acetoxyacids, process for their synthesis

摘要

2,5-Diaryl-1,3,4-oxadiazoles containing hydroxy ester, hydroxy acid and acetoxy acid endings, of formula: IMAGE in which R1 represents a hydroxyl or acetyl radical and R2 represents a carboxyl radical and where R1 and R2 preferably simultaneously occupy the 3 and 3' or 4 and 4' positions. The hydroxy esters are prepared by cyclisation of the corresponding diaromatic dihydrazide and the hydroxy acids are obtained by saponification of the above hydroxy esters.