Novel 2-substituted alkyl-3-carboxycarbapenem as an antibiotic, a process for the preparation thereof, a therapeutic method using the same, and a pharmaceutical composition containing the same

摘要

The invention relates to new 2-substituted alkyl-3-carboxy carbapenems having the formula: CHEM with R1, R2, R3, X and Y defined in the specification as antibiotics and beta lactamase inhibitors produced by a novel Michael addition-elimination reaction of a substituted allyl azetidinone in the reaction shown: CHEM with Q defined in the specification.r