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METHOD FOR PREPARATION OF POLYPEPTIDE HAVING HUMAN GAMMA INF ACTIVITY
METHOD FOR PREPARATION OF POLYPEPTIDE HAVING HUMAN GAMMA INF ACTIVITY
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机译:具有人类γ-干扰素活性的多肽的制备方法
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摘要
Partial sequences of human- gamma -interferon, comprising aminoacid sequences 5 to 127, 1 to 127 and 5 to 146, having biological activity. These partial sequences can be obtained by a genetic engineering process, for which purpose the appropriate DNA sequences are chemically synthesized. The DNA sequences are incorporated in hybrid plasmids, and the latter are introduced into host organisms and their expression is induced there. The biologically active polypeptides are suitable, as is human- gamma -interferon, for medicaments.
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