FOR SYNTHESIS OF 6-HYDROXYALKYL-2,3- DIMETHOXY-5-METHYL-1,4-BENZOQUINONE

摘要

A method for producing a compound of the formula: CHEM [wherein R1 and R2 each stand for a lower alkyl group; n denotes an integer of 0 to 21; X stands for hydrogen atom or an optionally protected hydroxyl group; and Y stands for an optionally protected hydroxyl group], which comprises by reducing an ester compound of the formula: CHEM [wherein R1, R2, n, X and Y are of the same meaning as defined above, and R3 stands for a lower alkyl group] with a mixture of sodium borohydride and aluminum chloride, gives the desired compound in a high yield, and is advantageous from the industrial point of view.