composition and method for the diagnosis of iga nephropathy.

摘要

PCT No. PCT/SE88/00240 Sec. 371 Date Jan. 8, 1990 Sec. 102(e) Date Jan. 8, 1990 PCT Filed May 9, 1988 PCT Pub. No. WO88/08983 PCT Pub. Date Nov. 17, 1988.A method for the diagnosis of IgA nephropathy using a specific binding reaction comprising the steps: a) preparing a substrate capable of binding fibronectin or IgA b) contacting the substrate resulting from step a) with a sample of body fluid drawn from a patient subject to diagnosis to bind any fibronectin-IgA-complex present in said sample to the substrate, and c) determining the presence of complex bound to the substrate using the reaction between the exposed part of such bound complex and a corresponding antibody thereto; and a diagnostic kit for use in such diagnosis.