4 - chlorine - 3 - sulfamoyl - benzoesaeure - hydrazides, processes for their manufacture, and use of these compounds arzneimittelpraeparate containing compounds for the manufacture of diuretic and salzentziehend acting arzneimittelpraeparaten.

摘要

The novel compounds according to the invention correspond to the general formula I …IMAGE… in which… R represents hydrogen, a trifluoromethyl or carboxyl group, an alkoxycarbonyl group having 2-5 carbon atoms, a cyano, benzoyl or sulphamoyl group or an alkylsulphonyl group having 1-4 carbon atoms,… R1 represents hydrogen, an alkylthio or alkylsulphonyl group each having 1-4 carbon atoms, a straight or branched alkyl group having 1-4 carbon atoms, or a benzylthio, benzylsulphonyl, phenyl, hydroxyl or thiol group and… R2 represents hydrogen or chlorine. …??The novel compounds act as diuretics and saluretics and have a hypotensive action.