investigation of the degradation of collagen type iii.

摘要

PCT No. PCT/FI88/00066 Sec. 371 Date Dec. 5, 1989 Sec. 102(e) Date Dec. 5, 1989 PCT Filed May 2, 1988 PCT Pub. No. WO88/08980 PCT Pub. Date Nov. 17, 1988.The degradation of type III collagen in the body is quantitatively determined by measuring the concentration of the liberated aminoterminal telopeptide region of the type III collagen molecule in the body fluid by a specific immunological method. This degredation product is resistant to further degradation and can thus be found in body fluids e.g. in serum or urine. For the determination the telopeptide region must be isolated from a human source e.g. from uterine leiomyoma.