6H-Pyrido3,2-bcarbazole derivatives, process for their preparation and their application in therapeutics

摘要

Antineoplastic derivatives corresponding to the formula: IMAGE in which: - R2 = H, halogen, OH, CH3O or carbethoxyoxy, and - the -A----B- linkage represents (i) IMAGE , in which case R3 denotes: *) either OH or Cl; R and R1, which can be identical or different, each then representing: H, C1-C4 alkyl; methoxymethyl or methoxyethyl; -(CH2)n-COR4 where n = 0, 1, 2 or 3 and R4 = OH, C1-C4 alkoxy or hydrazino; or benzyl; *) or C1-C4 alkoxy or C2-C5 acyloxy; R and R1, which can be identical or different, then representing H or C1-C4 alkyl; or ii) IMAGE , in which case R3 = OH and R1 = H. m