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Hybrid ligand directed to activation of cytotoxic effector T lymphocytes and target associated antigen
Hybrid ligand directed to activation of cytotoxic effector T lymphocytes and target associated antigen
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机译:定向于激活细胞毒性效应T淋巴细胞和靶标相关抗原的杂合配体
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摘要
A hybrid ligand molecular composed of an antibody combining site that binds to a T cell receptor complex structure and is capable of activating cytotoxic T lymphocytes linked to a target cell-specific antibody is disclosed. This ligand molecule can bind to an antigen on the surface of a target cell and to cytotoxic effector T lymphocyte cell receptor complex structures. A composition and a method for killing tumor cells with the hybrid ligand molecule of this invention are provided.
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