Sensitizing multidrug resistant cells to antitumor agents

摘要

A method for sensitizing multidrug resistant cells to antitumor agents comprosing contacting multidrug resistant cells, with an effective amount of a compound of the formula ##STR1## wherein n is 1, 2 or 3, X is CF.sub. 3, --O--CH.sub.3, Br, I, Cl, H, W and S--CH.sub.3 and R.sup.1 and R.sup.2, independently of each other are --CH.sub.3 --CH.sub. 2 --CH.sub.3, CH.sub. 2 CH.sub.2 OHCH.sub.2 OH, or NR.sup.1 R.sup.2 form a ring ##STR2## wherein R.sup.3 is --CH.sub.3, CH.sub.2 --CH.sub.3, --H, CH.sub.2 OH and CH.sub.2 CH.sub.2 OH.