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Method for the stimulation of cell growth and the inhibition of cell proliferation by the utilization of selenodithiols such as selenodiglutathione

机译:利用硒二谷胱甘肽等硒二硫醇刺激细胞生长和抑制细胞增殖的方法

摘要

This invention relates to the inhibition of cell proliferation in mammalian host organisms. More particularly the invention relates to the utilization of selenodithiol compositions, particularly selenodiglutathione (GSSeSG) within a narrow concentration range, in which it is both effective as an inhibitor of cancer tumor cell proliferation in mammals, particularly in the prevention of neoplastic cell division in humans, while substantially non toxic outside this narrow range to the treated host organism. The invention also relates to a method for stimulating cellular proliferation at lower concentration of selenodiglutathione.
机译:本发明涉及在哺乳动物宿主生物中细胞增殖的抑制。更具体地,本发明涉及在窄浓度范围内的硒二硫醇组合物,特别是硒二谷胱甘肽(GSSeSG)的利用,其中硒二硫醇组合物在哺乳动物中均有效地作为癌症细胞增殖的抑制剂,特别是在预防人类肿瘤细胞分裂方面。 ,但在这个狭窄范围之外对治疗的宿主生物基本上无毒。本发明还涉及在较低浓度的硒二谷胱甘肽下刺激细胞增殖的方法。

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