Optical fiber sensors for continuous monitoring of biochemicals and related method

摘要

A device and method for measuring properties of certain substances such as analytes are provided. The device includes a probe housing having an optical fiber associated therewith. The housing is capped on one end by a porous membrane which is permeable to the analyte being studied. The housing also includes a reflective surface member disposed between the end of the optical fiber and the membrane, thereby defining a chamber. The reflective surface member does not allow light to be transmitted into or out of the chamber. However, a dye-labeled analog- analyte can permeate the reflective surface member and thereby allow a measurement to be taken which is related to the concentration of the analyte being studied. An embodiment for use in vivo is provided. A related method is also provided.