首页> 外国专利> Although the metal of the poisonous level which consists of 1 hidorokishipirido 2 on or that salt, to internal of the patient is made to decrease the effective medicine constituent

Although the metal of the poisonous level which consists of 1 hidorokishipirido 2 on or that salt, to internal of the patient is made to decrease the effective medicine constituent

机译:虽然在其上或该盐上含有由1个hidorokishipirido 2组成的有毒水平的金属,但会降低患者体内的有效药物成分

摘要

Compounds which are a 1-hydroxypyrid-2-one in which one or more of the hydrogen atoms attached to ring carbon atoms are replaced by a substituent selected from aliphatic acyl, aliphatic amide, aliphatic amine, carboxy, cyano, aliphatic ester, halogen, hydroxy and sulpho groups, alkoxy groups and alkoxy groups substituted by an alkoxy, aliphatic amide, aliphatic amine, aliphatic ester, halogen or hydroxy group, aliphatic hydrocarbon groups and aliphatic hydrocarbon groups substituted by an alkoxy, aliphatic ester, halogen or hydroxy group, but excluding compounds in which said replacement of hydrogen atoms in the compound is effected only by substituents selected from aliphatic hydrocarbon groups, halogen groups and aliphatic hydrocarbon groups substituted by a halogen group, or a salt thereof containing a physiolgically acceptable ion or ions, are of value in the treatment of patients having a toxic concentration of a metal, particularly iron, in the body whilst the iron complexes of such compounds are of value in the treatment of iron deficiency anaemia.
机译:1-羟基吡啶-2-酮化合物,其中一个或多个与环碳原子相连的氢原子被选自脂族酰基,脂族酰胺,脂族胺,羧基,氰基,脂族酯,卤素,被烷氧基,脂族酰胺,脂族胺,脂族酯,卤素或羟基取代的羟基和磺基,烷氧基和烷氧基,被烷氧基,脂族酯,卤素或羟基取代的脂族烃基和脂族烃基,但是排除其中仅通过选自脂族烃基,卤素基团和被卤素基团取代的脂族烃基的取代基或其包含生理上可接受的离子的盐进行取代的化合物,所述化合物中的氢原子的取代是有价值的用于治疗体内具有金属特别是铁的毒性浓度而s的铁络合物的患者许多化合物在治疗缺铁性贫血中具有价值。

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