PURPOSE:To obtain an aspirin enteric table useful as an analgesic and an antipyretic having improved stability by suppressing hydrolysis of aspirin caused by mutual action of aspirin, an enteric film agent and a plasticizer added to the agent. CONSTITUTION:Aspirin is blended with a proper medical additive such as excipient or lubricant, granulated or tabulated to give tablets and a protecting layer consisting only of suger is made between the tablets and an enteric film comprising an enteric film agent such as hydroxypropylmethyl cellulose phthalate or a methyl methacrylate-methyl acrylate copolymer and a plasticizer such as glycerol fatty acid ester, triacetin or citric acid triethyl ester to give an aspirin enteric tablet showing excellent medicinal effects because hydrolysis of aspirin is suppressed even if allowed to stand under a condition at high temperature, e.g. 50 deg.C and aspirin is stably preserved for a long period of time.
展开▼