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ROD FOR PREVENTING OUTFLOW OF TEARS

机译:防止眼泪流出的棒

摘要

PURPOSE: To obtain the rod for preventing the outflow of the tears which is less fluctuated in a dissolving speed by using a polymer having the repeating unit expressed by general formula. ;CONSTITUTION: The polymer consisting of the formula (R is hydrogen or methyl; (n) is 1 or 2; at least one piece of R is hydrogen when (n) is 2) is obtd. by subjecting a monomer to a ring opening polymn. at 75 to 130°C in the presence of an org. metallic catalyst, such as diethyl zinc as shown in, for example, US Patent Specification No. 4052988. The resulted polymer is melt spun by using a plunger extruder, etc., and is cooled to solidify; thereafter, the extruded polymer is cut to a desired length, by which the rod for preventing the outflow of the tears is obtd. A dry eye symptom is decreased by using such rod for preventing the outflow of the tears. Since the dissolution speed is uniform, the management of an insertion schedule is easy and in addition, the unstability as to bioaffinity is lessened.;COPYRIGHT: (C)1993,JPO&Japio
机译:用途:通过使用具有通式表示的重复单元的聚合物,获得用于防止在溶解速度上波动较小的泪液流出的棒。 ;组成:由式(R为氢或甲基;(n)为1或2;当(n)为2)时至少一个R为氢的聚合物。通过使单体经受开环polymn。在组织存在下于75至130°C下进行。金属催化剂,例如美国专利说明书4052988中所示的二乙基锌。通过使用柱塞挤出机等将所得的聚合物熔融纺丝,并冷却以使其固化。此后,将挤出的聚合物切成所需的长度,由此使用于防止泪液流出的棒被拉长。通过使用这种杆防止眼泪流出,可以减轻干眼症状。由于溶出速度均匀,插入时间表的管理容易,此外,减少了生物亲和力的不稳定性。;版权所有:(C)1993,JPO&Japio

著录项

  • 公开/公告号JPH0592015A

    专利类型

  • 公开/公告日1993-04-16

    原文格式PDF

  • 申请/专利权人 ASAHI CHEM IND CO LTD;

    申请/专利号JP19910253659

  • 发明设计人 SUZUKI KEIJI;FUKUDA KUNIO;

    申请日1991-10-01

  • 分类号A61F2/14;A61L27/00;

  • 国家 JP

  • 入库时间 2022-08-22 05:13:50

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