首页> 外国专利> Process for detecting the presence of a sequence variant of the - globin locus of ggama that defines a allele C in a sample and to determine the locus of ggama - globin genotype of an individual.Probe of SSO; the panel of at least two probes of SSO; utilizavel kit to determine the genotype of an individual in ggama - globin locus; and method for the delivery of forensic evidence for derivacaoA sample

Process for detecting the presence of a sequence variant of the - globin locus of ggama that defines a allele C in a sample and to determine the locus of ggama - globin genotype of an individual.Probe of SSO; the panel of at least two probes of SSO; utilizavel kit to determine the genotype of an individual in ggama - globin locus; and method for the delivery of forensic evidence for derivacaoA sample

机译:用于检测在样品中定义等位基因C的伽马-球蛋白基因座序列变异体的存在并确定个体的伽马-球蛋白基因座的方法。至少两个SSO探针组; utilizavel试剂盒,用于确定在ggama-globin基因座中个体的基因型;派生样本的法医证据的方法和方法

摘要

Methods and reagents for determining an individual's genotype at the G gamma -globin locus with respect to a set of three alleles using sequence-specific oligonucleotide probes enable one to type samples from a variety of sources, including samples comprising RNA or cDNA templates, and can be applied to nucleic acids in which a target region spanning the polymorphism has first been amplified. This three-allele system facilitates typing tissue for determining individual identity and has application in the field of forensic science.
机译:使用序列特异性寡核苷酸探针确定相对于一组三个等位基因在γ-球蛋白基因座的个体基因型的方法和试剂,使人们能够从多种来源中分选样品,包括包含RNA或cDNA模板的样品,并且可以应用于其中首先扩增出跨越多态性的靶区域的核酸。该三等位基因系统有助于键入组织以确定个人身份,并已在法医学领域中应用。

著录项

  • 公开/公告号BR9201715A

    专利类型

  • 公开/公告日1993-08-10

    原文格式PDF

  • 申请/专利权人 F. HOFFMANN-LA ROCHE AG.;

    申请/专利号BR19929201715

  • 发明设计人 RANDALL K. SAIKI;SHANAVAZ L. NASARABADI;

    申请日1992-05-07

  • 分类号G01N33/68;C12N15/11;

  • 国家 BR

  • 入库时间 2022-08-22 05:12:31

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