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PHARMACEUTICAL PREPARATION FOR TREATING CARDIAL AND VASCULAR HYPERTROPHY AND HYPERPLASIA

机译:药物制剂治疗心,血管肥大和增生

摘要

The invention relates to a method for the treatment of cardiac and of vascular hypertrophy and hyperplasia by administration of angiotensin converting enzyme inhibitors. Administration of compounds of the formula I IMAGE (I) in which n is 1 or 2, R, R1, R2 and R3 are identical or different and each is hydrogen or an organic radical, and R4 and R5 form, together with the atoms carrying them, a mono-, bi- or tricyclic heterocyclic ring system, is preferred. The invention additionally relates to angiotensin converting enzyme inhibitors and to agents containing these for administration for the treatment of the abovementioned diseases.
机译:本发明涉及通过给予血管紧张素转化酶抑制剂来治疗心脏以及血管肥大和增生的方法。式(I)的化合物的给药,其中n为1或2,R,R 1,R 2和R 3相同或不同,并且各自为氢或有机基团,并且R 4和R 5与优选带有它们的原子,即单,双或三环杂环系统。本发明还涉及血管紧张素转化酶抑制剂和包含这些抑制剂的用于治疗上述疾病的药剂。

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