首页> 外国专利> Oejenlaegemiddel containing thiomersal as a preservative, and the use of 2-amino-2-hydroxymethyl-1,3-propanediol or a homologue thereof in the manufacture of Hypotonic or oejengeler for the stabilization of the preservative thiomersal

Oejenlaegemiddel containing thiomersal as a preservative, and the use of 2-amino-2-hydroxymethyl-1,3-propanediol or a homologue thereof in the manufacture of Hypotonic or oejengeler for the stabilization of the preservative thiomersal

机译:含有硫柳汞作为防腐剂的Oejenlaegemiddel,以及2-氨基-2-羟甲基-1,3-丙二醇或其同系物在制备用于稳定防腐剂硫柳汞的Hypotonic或oejengeler中的用途

摘要

The invention relates to the stabilization of mercury-containing preservatives in liquid or gel-form ophthalmic medicaments. This stabilization against chemical decomposition after the preservative has become deposited on the inner walls of the plastics containers is achieved by adding to the formulation 2-amino-2-hydroxymethyl-1,3-propanediol or a homologue thereof having up to 10 carbon atoms.
机译:本发明涉及液体或凝胶形式的眼科药物中含汞防腐剂的稳定化。通过在制剂中加入2-氨基-2-羟甲基-1,3-丙二醇或其具有至多10个碳原子的同系物,可以实现在防腐剂沉积在塑料容器内壁上之后防止化学分解的稳定性。

著录项

  • 公开/公告号DK164643C

    专利类型

  • 公开/公告日1992-12-21

    原文格式PDF

  • 申请/专利权人 DISPERSA AG;

    申请/专利号DK19870001579

  • 发明设计人 DOULAKAS JOHANN;

    申请日1987-03-27

  • 分类号A61K47/24;

  • 国家 DK

  • 入库时间 2022-08-22 05:12:16

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