PROCESS FOR PRODUCING 1,2,4-TRIAZOLO/1,5-A/PYRIMIDINE DERIVATIVES AND THEIR DERIVATIVES CONDENSED WITH CARBOCYCLE, TETRAHYDROTHIOPYRAN AND PIPERIDINE RING

摘要

Compounds of formula CHEM wherein Q represents H or a heterocyclic group containing nitrogen and/or oxygen atoms, S(O)p - R3 wherein p is 0, 1 or 2 and R3 is optionally substitutes alkyl, alkenyl or phenylalky, or optionally substitute phenyl, or a group CHEM wherein R4 and R5 represent hydrogen, alkyl, alkenyl, phenylalkyl or di-(alkyl)-aminoalkyl, R1 and R2 represent hydrogen or alkyl or R1 and R2 together form a group CHEM wherein Y stands for a CH2 group, sulfur or a group of the formula CHEM in which R6 denotes hydrogen or phenylalkyl, n and m is 0-5 and Z represents a group CHEM in which R7 and R8 represent hydrogen, alkyl, optionally carrying hydroxy, carboxy, amino, morpholinocarbonyl, [4-(2'-{hydroxy}-ethyl)-piperazin-1'-yl]-carbonyl and/or alkoxycarbonyl or optionally carrying a heterocyclic group containing nitrogen and/or oxygen atoms alkenyl, cycloalkyl, adamantyl or phenylalkyl, alkylaminoalkyl and di-(alkyl)-aminoalkyl; or R7 and R8 form a group CHEM in which j and k represent 1, 2 or 3 and W stands for oxygen, a CHEM a CHEM or a group of the formula CHEM in which R10 denotes hydrogen, alkoxycarbonyl oroptionally substituted alkyl, or stands for a group of the formula - S - R9 wherein R9 represents alkyl, optionally substituted by an alkoxycarbonyl-group.