process for preparation of crystalline salts of addition with acid ester of 1 - (2,2 - dimethylpropionyloxy) ethyl 3 - cepheme acid - 4 - carboxylic acid, in the form of pure diastereoisomeres

摘要

The invention relates to crystalline acid addition salts of the two diastereomers of the 1-(2,2-dimethylpropionyloxy)ethyl ester of 3-cephem-4-carboxylic acid of the general formula II IMAGE in which X represents the anion of a physiologically acceptable, mono- or polybasic, inorganic or organic acid and the group =N-OH is in the syn position, pharmaceutical preparations active against bacterial infections and which contain such cephem derivatives, a process for the preparation of the cephem derivatives, and the use of the cephem derivatives for the control of bacterial infections.