pharmaceutical preparations.the influence demaagzuurafscheiding possess at least a qu anidinothiazoolderivaat bevattenalsmede as active substance for use in such preparations suitable quanidinothiazoopolyacrylic.

摘要

Novel guanidinothiazole compounds of the general formula IMAGE wherein R represents a hydrogen atom or a lower alkyl group, R1 represents an amino group, a lower alkyl group, a halogeno lower alkyl group, a substituted- or unsubstituted-aryl group, a mono- or di-lower alkylamino group, an arylamino group or an aralkylamino group, R2 represents a hydrogen atom, a lower alkyl group, a lower alkenyl group or a lower alkynyl group, Y represents a sulfur atom or a methylene group, m and n, each represents an integer of 1-3, and the pharmacologically acceptable acid addition salts thereof, they are useful as gastric acid secretion inhibitors.