Compound and process for its preparation, and use of said compound, pharmaceutical compositions and method of treatment of rheumatoid arthritis, diseases of immune origin inflamatorias chronicles and not immune and cancer

摘要

The Application relates to the products …IMAGE… in which: … …  - R1 represents …IMAGE… R13, R14 or R15 represent H, halogen or (C1-3)alkyl and n = 1, 2 or 3, …  - R2 represents H or (C1-3)alkyl, …  - R3, R4, R5, R6 and R7 represent H, halogen, NO2, CN, (C1-6 )alkyl, CO-(C2-6)alkyl, (C3-6)cycloalkyl, (C1-6)alkoxy or -alkylthio or -(CH2)m-CF3, -O-(CH2)m-CF3, -S-(CH2)m-CF3 , or a -CF2-Hal, -OCF2-Hal, …IMAGE… …IMAGE… or …IMAGE… radical with R8, R9, R10, R11 and R12 having the values shown for R3, R 4, R5, R6 and R7, or form -O-CH2-O, … to their tautomeric forms and to their salts, as well as to a process for their preparation, to their application as medicaments, especially anti-inflammatories, and to the pharmaceutical compositions which contain them.