DETERGENT-COMPLEXED HUMAN RHINOVIRUS RECEPTOR: (INTERCELLULAR ADHESION MOLECULE-1 (ICAM-1) FRAGMENTS)
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机译:洗涤剂复杂的人鼻病毒受体:(细胞间粘附分子-1(ICAM-1)片段)
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摘要
A water soluble human rhinovirus (HRV) major receptor preparation comprising detergent-complexed glycoprotein isolated from animal cells, preferably mammalian cells, that express the HRV major receptor and which exhibits the ability to bind to HRV capsids to substantially reduce infectivity of the virus. The purified, water soluble receptor is obtained by extracting cells expressing the receptor with detergent and isolating the solubilized detergent-glycoprotein complexes by binding to monoclonal antibody selective for the HRV receptor protein.
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