Sodium 2- (4-isobutyrylphenyl) propionate and S (+) - 2- (4-isobutyrylphenyl) propionate, Sodium propionate, Sodium 2- (4-isobutyrylphenyl) propionate, - (4-isobutylphenyl) -propionic acid

摘要

The use of S(-)sodium 2-(4-isobutylphenyl)-propionate (the sodium salt of S(+)-ibuprofen) in pharmaceutical compositions for the treatment of inflammation, pain and pyrexia is described. Preferred compositions comprise S(-)sodium 2-(4-isobutylphenyl)-propionate dihydrate.Processes to prepare S(-)sodium 2-(4-isobutylphenyl)propionate and its use in a process to prepare S(+) 2-(4-isobutylphenyl)propionic acid of high enantiomeric purity are also described.