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Synthetic peptide derived from human lipocortin V and its use.

机译:源自人脂皮质激素V的合成肽及其用途。

摘要

The synthetic peptide with the formula (I): H-Ser-His-Leu-Arg-Lys-Val-Phe-Asp-Lys-OH and its organic or inorganic salts physiologically acceptably are new. The synthetic peptide (I), whose amino acid sequence corresponds to that of segment 204-212 of the human lipcortin V, shows in in-vitro conditions the ability to inhibit the release of E2 prostaglandin and in live conditions has an anti-inflammatory effect. Said peptide (I) and its organic and inorganic salts are used as therapeutic reactants in treating inflammatory, dermatological and collagen infections.
机译:具有式(I):H-Ser-His-Leu-Arg-Lys-Val-Phe-Asp-Lys-OH的合成肽及其生理上可接受的有机或无机盐是新的。氨基酸序列与人脂皮质激素V片段204-212相对应的合成肽(I)在体外条件下具有抑制E2前列腺素释放的能力,而在活体条件下则具有抗炎作用。所述肽(I)及其有机盐和无机盐在治疗炎症,皮肤病学和胶原蛋白感染中用作治疗反应物。

著录项

  • 公开/公告号IT1236970B

    专利类型

  • 公开/公告日1993-05-07

    原文格式PDF

  • 申请/专利权人 SCLAVO S.P.A.;

    申请/专利号IT19890022251

  • 申请日1989-11-03

  • 分类号5C07CA;5A61KB;

  • 国家 IT

  • 入库时间 2022-08-22 05:10:03

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