首页> 外国专利> Tranquiliser compounds made through 7-chlorine-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4 benzodiazepine-2-one with cyclodextrin complexes, their preparation and relative pharmaceutical composition.

Tranquiliser compounds made through 7-chlorine-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4 benzodiazepine-2-one with cyclodextrin complexes, their preparation and relative pharmaceutical composition.

机译:通过7-氯-5-(2-氯苯基)-1,3-二氢-3-羟基-2H-1,4-苯并二氮杂-2-酮与环糊精复合物制得的镇静剂化合物,其制备方法和相关药物组成。

摘要

Compounds made by mixing 7-chlorine-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4 benzodiazepine-2-one with a cyclodextrin chosen between α, β, γ, dimethyl-β, or hydroxypropyl-β cyclodextrin.The above-mentioned compound offers better tranquilizer, hypnotic, muscle relaxant and anticonvulsant effects in respect to the corresponding starting qualities administered as such, and better stability compared to similar products.
机译:通过将7-氯-5-(2-氯苯基)-1,3-二氢-3-羟基-2H-1,4苯二氮杂-2-酮与选自α,β,γ,二甲基-β的环糊精混合制得的化合物就这样给予的相应起始质量而言,上述化合物提供了更好的镇定,催眠,肌肉松弛和抗惊厥作用,并且与类似产品相比具有更好的稳定性。

著录项

  • 公开/公告号IT1237510B

    专利类型

  • 公开/公告日1993-06-08

    原文格式PDF

  • 申请/专利权人 MAGIS FARMACEUTICI S.P.A.;

    申请/专利号IT19890022200

  • 发明设计人 PURICELLI LAURA;

    申请日1989-10-31

  • 分类号5A61KA;

  • 国家 IT

  • 入库时间 2022-08-22 05:10:01

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