process for the preparation of genetic constructs for the expression of nervous growth factor in eukaryotic cells.

摘要

This invention relates to a process for obtaining, from transformed cells, the polypeptide called nerve growth factor ( beta -NGF), and more precisely to the process for obtaining, by recombinant DNA technology using genetic constructions insertible in appropriate eukaryotic cell lines, the biologically active human mature form ( beta -subunit).