New allyl esters and their application to form solid phase systems for solid phase reactions. Reserve art. 167.2 pec.

摘要

The invention relates to an allyl ester having the formula (I) can react with a carrier (F) containing a functional group B is used for the synthesis SYSTEMS PHASES SOLID CONTAINING side chains allylic, obtained in solution easily and is bound to a solid support, DESCRIBE THE APPLICATION OF SOLID PHASE PRODUCED FOR solid phase peptide and glycopeptide AND RES / A the peptide and glycopeptide obtained, which can dissociate from polymers SUPPORTS AND MILD CONDITIONS WHERE NO NO DISASSOCIATION IS PRESENTED IN glycosidic conformations OR AMONERIZACION. Where: A GROUP; AYB they react under CONDENSATION, ADDITION AND SHAPING A LINK BETWEEN THE MATERIAL SUPPORT AND THE REST OF FORMULA (II); R1 and R2 same or different hydrogen, alkyl, aryl or halogen; R3 a linking group, R A REST ORGANICO; Acyl acyloxy group, an acid OTHER CARBON aliphatic or RCO-; X acyloxy group; EY, O, NH SO.