首页> 外国专利> Triterpene saponins having antiinflammatory, mucolytic and antiedemic activity, process for their preparation and pharmaceutical compositions containing them.

Triterpene saponins having antiinflammatory, mucolytic and antiedemic activity, process for their preparation and pharmaceutical compositions containing them.

机译:具有抗炎,粘液溶解和抗水肿活性的三萜皂苷,其制备方法和含有它们的药物组合物。

摘要

Saponins TRITERPENES of formula (I) wherein R1 is OH and R2 is HU CHAIN ​​OR ALTERNATIVELY TETRASACARIDA pentasaccharide, have antiinflammatory ACTIVITIES, mucolytic and anti-oedematous. SUCH saponins isolated from ROOTS AND BARK CROSSOPTERIX febrífuga, FOR EXAMPLE, precipitating, complexed with cholesterol or sitosterol, an alcohol extract of plant material and separating the precipitate by partitioning between a solvent nonpolar subtracts the complexing agent AND POLAR solvent in which are soluble saponins.
机译:式(I)的皂苷三萜类化合物,其中R1是OH并且R2是HU链或另外的四SA螨五糖,具有抗炎活性,粘液溶解和抗水肿。从根和树皮CROSSOPTERIXfebrífuga中分离出的这种皂苷,例如与植物性物质的醇提取物胆固醇,谷甾醇复合并沉淀,并通过在非极性溶剂之间进行分配来分离沉淀物,从而减去了可溶性皂苷的络合剂和POLAR溶剂。

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